
Publications
2026
Typical and Atypical Frequency-Based Subtypes of EEG Reactivity in Hospitalized Patients and Association With Comorbidities and OutcomesHwang J, Cho SM, Johnson EL, Kimchi EY, Schuele SU, Habela CW, Ritzl EK.
Neurology, 2026. PubMed
2025
Covert Critical Illness Encephalopathy: Impairments That Escape Detection by Guideline Recommended, Protocolized AssessmentsShirodkar R, Bourgeois IJ, Kim M, Kimchi EY, Liotta EM, Maas MB.
Crit Care Med, 2025. PubMed
Daily Automated Prediction of Delirium Risk in Hospitalized Patients: Model Development and Validation
Shaw KM, Shao YP, Ghanta M, Junior VM, Kimchi EY, Houle TT, Akeju O, Westover MB.
JMIR Med Inform, 2025. PubMed
Five-Decade Prevalence of Delirium in Pneumonia, Risk Factors, and Associated Mortality: A Systematic Review and Meta-Analysis
Juarez-Martinez EL, Araia A, Prasad D, Dhar S, Nandoliya K, Sherrington IG, Zhao C, Wescott A, Pickens CI, Wunderink RG, Kimchi EY.
medRxiv, 2025. PubMed
Occurrence Rates of Delirium in Brain Tumor Patients: A Systematic Review and Meta-Analysis
Tentor Z, Finnemore A, Miller PJ, Davis J, Juarez Martinez E, Lindvall C, Kimchi EY, Rhee JY.
Cancers (Basel), 2025. PubMed
Separable dorsal raphe dopamine projections mimic the facets of a loneliness-like state
Lee CR, Matthews GA, Lemieux ME, Wasserlein EM, Borio M, Miranda RL, Keyes LR, Schneider GP, Jia C, Tran A, Aloboudi F, Chan MG, Peroni E, Pereira G, López-Moraga A, Pallé A, Kimchi EY, Padilla-Coreano N, Wichmann R, Tye KM.
Elife, 2025. PubMed
Five-decade prevalence of delirium in pneumonia, risk factors and associated mortality: a systematic review and meta-analysis
Juarez-Martinez EL, Araia A, Prasad D, Dhar S, Nandoliya K, Sherrington IG, Zhao C, Wescott A, Pickens CI, Wunderink RG, Kimchi EY.
Eur Respir Rev, 2025. PubMed
From reactive to proactive: Continuous protein monitoring for preventive health care
Donnelly JM, Neff RA, Sedlack AJH, Juska VB, Ayala-Cardona LF, Bass J, McNally EM, Shah SJ, Alshurafa N, Kimchi EY, Budinger GRS, Kelley SO.
Science, 2025. PubMed
Clinical Reasoning: A 66-Year-Old Female Patient With Rapidly Progressive Memory Changes
Fokas JA, Guo K, Mejia Bautista M, Kimchi EY, Dixit K, Brat D, Jia DT.
Neurology, 2025. PubMed
Intranasal cocaine self-administration in male mice
Erickson KR, Quan Y, Farahbakhsh ZZ, Branthwaite HE, Song K, Kim JD, Lee JJ, Gibson-Corley KN, Kimchi EY, Siciliano CA.
Nat Commun, 2025. PubMed
2024
Successful aging after elective surgery II: Study cohort descriptionWard M, Hshieh TT, Schmitt EM, Arnold SE, Cavallari M, Dickerson BC, Dillon ST, Fong TG, Jones RN, Libermann TA, Pascual-Leone A, Shafi MM, Touroutoglou A, Weng K, Xu G, Earp BE, Kunze L, Lange J, Vlassakov K, Marcantonio ER, Inouye SK, Travison TG; SAGES II Study Team.
J Am Geriatr Soc, 2024. PubMed
Scaling behaviours of deep learning and linear algorithms for the prediction of stroke severity
Bourached A, Bonkhoff AK, Schirmer MD, Regenhardt RW, Bretzner M, Hong S, Dalca AV, Giese AK, Winzeck S, Jern C, Lindgren AG, Maguire J, Wu O, Rhee J, Kimchi EY, Rost NS.
Brain Commun, 2024. PubMed
Reward contingency gates selective cholinergic suppression of amygdala neurons
Kimchi EY, Burgos-Robles A, Matthews GA, Chakoma T, Patarino M, Weddington JC, Siciliano C, Yang W, Foutch S, Simons R, Fong MF, Jing M, Li Y, Polley DB, Tye KM.
Elife, 2024. PubMed
Investigating delirium in stroke with an EEG lens: Focal lesions with global impact?
Juárez Martínez EL, Kimchi E.
Clin Neurophysiol, 2024. PubMed
International Delirium Pathophysiology & Electrophysiology Network for Data sharing (iDEPEND)
Sanders RD, Watne L, Roberson SW, Kimchi EY, Slooter AJC, Cunningham C, Nourski KV, Palanca BJA, Lennertz R, Banks MI.
BJA Open, 2024. PubMed
Prediction of stroke severity: systematic evaluation of lesion representations
Bonkhoff AK, Cohen AL, Drew W, Ferguson MA, Hussain A, Lin C, Schaper FLWVJ, Bourached A, Giese AK, Oliveira LC, Regenhardt RW, Schirmer MD, Jern C, Lindgren AG, Maguire J, Wu O, Zafar S, Rhee JY, Kimchi EY, Corbetta M, Rost NS, Fox MD; MRI‐GENIE and GISCOME Investigators and the International Stroke Genetics Consortium.
Ann Clin Transl Neurol, 2024. PubMed
The Framing and Scope of Altered Mental Status and Delirium
Albin CSW, Kimchi EY.
Semin Neurol, 2024. PubMed
2023
Thalamus sends information about arousal but not valence to the amygdalaLeppla CA, Keyes LR, Glober G, Matthews GA, Batra K, Jay M, Feng Y, Chen HS, Mills F, Delahanty J, Olson JM, Nieh EH, Namburi P, Wildes C, Wichmann R, Beyeler A, Kimchi EY, Tye KM.
Psychopharmacology (Berl), 2023. PubMed
Potentiated cholinergic and corticofugal inputs support reorganized sensory processing in the basolateral amygdala during auditory threat acquisition and retrieval
Asokan MM, Watanabe Y, Kimchi EY, Polley DB.
bioRxiv, 2023. PubMed
Giant Cell Arteritis Presenting With Multiple Cranial Neuropathies – Case Report
Ye JJ, Bouffard MA, Brooks E, Hung YP, Kimchi EY.
Neurohospitalist, 2023. PubMed
Sound and light levels in intensive care units in a large urban hospital in the United States
Leone MJ, Dashti HS, Coughlin B, Tesh RA, Quadri SA, Bucklin AA, Adra N, Krishnamurthy PV, Ye EM, Hemmige A, Rajan S, Panneerselvam E, Higgins J, Ayub MA, Ganglberger W, Paixao L, Houle TT, Thompson BT, Johnson-Akeju O, Saxena R, Kimchi E, Cash SS, Thomas RJ, Westover MB.
Chronobiol Int, 2023. PubMed
Associations between early in-hospital medications and the development of delirium in patients with stroke
Ryan SL, Liu X, McKenna V, Ghanta M, Muniz C, Renwick R, Westover MB, Kimchi EY.
J Stroke Cerebrovasc Dis, 2023. PubMed
Automated detection of immune effector cell-associated neurotoxicity syndrome via quantitative EEG
Eckhardt CA, Sun H, Malik P, Quadri S, Santana Firme M, Jones DK, van Sleuwen M, Jain A, Fan Z, Jing J, Ge W, Danish HH, Jacobson CA, Rubin DB, Kimchi EY, Cash SS, Frigault MJ, Lee JW, Dietrich J, Westover MB.
Ann Clin Transl Neurol, 2023. PubMed
Potentiation of cholinergic and corticofugal inputs to the lateral amygdala in threat learning
Asokan MM, Watanabe Y, Kimchi EY, Polley DB.
Cell Rep, 2023. PubMed
2022
Physiological Assessment of Delirium Severity: The Electroencephalographic Confusion Assessment Method Severity Score (E-CAM-S)van Sleuwen M, Sun H, Eckhardt C, Neelagiri A, Tesh RA, Westmeijer M, Paixao L, Rajan S, Velpula Krishnamurthy P, Sikka P, Leone MJ, Panneerselvam E, Quadri SA, Akeju O, Kimchi EY, Westover MB.
Crit Care Med, 2022. PubMed
Associations Between Stroke Localization and Delirium: A Systematic Review and Meta-Analysis
Rhee JY, Colman MA, Mendu M, Shah SJ, Fox MD, Rost NS, Kimchi EY.
J Stroke Cerebrovasc Dis, 2022. PubMed
VE-CAM-S: Visual EEG-Based Grading of Delirium Severity and Associations With Clinical Outcomes
Tesh RA, Sun H, Jing J, Westmeijer M, Neelagiri A, Rajan S, Krishnamurthy PV, Sikka P, Quadri SA, Leone MJ, Paixao L, Panneerselvam E, Eckhardt C, Struck AF, Kaplan PW, Akeju O, Jones D, Kimchi EY, Westover MB.
Crit Care Explor, 2022. PubMed
Sleep Assessment in Critically Ill Adults: Established Methods and Emerging Strategies
Weinhouse GL, Kimchi E, Watson P, Devlin JW.
Crit Care Explor, 2022. PubMed
Learned Motor Patterns Are Replayed in Human Motor Cortex during Sleep
Rubin DB, Hosman T, Kelemen JN, Kapitonava A, Willett FR, Coughlin BF, Halgren E, Kimchi EY, Williams ZM, Simeral JD, Hochberg LR, Cash SS.
J Neurosci, 2022. PubMed
EEG-based grading of immune effector cell-associated neurotoxicity syndrome
Jones DK, Eckhardt CA, Sun H, Tesh RA, Malik P, Quadri S, Firme MS, van Sleuwen M, Jain A, Fan Z, Jing J, Ge W, Nascimento FA, Sheikh IS, Jacobson C, Frigault M, Kimchi EY, Cash SS, Lee JW, Dietrich J, Westover MB.
Sci Rep, 2022. PubMed
2021
Child Neurology: Intractable Epilepsy and Transient Deficits in a Patient With a History of Herpes Simplex Virus EncephalitisManzano GS, Danish HH, Chu CJ, Kimchi EY.
Neurology, 2021. PubMed
Electroencephalographic Abnormalities are Common in COVID-19 and are Associated with Outcomes
Lin L, Al-Faraj A, Ayub N, Bravo P, Das S, Ferlini L, Karakis I, Lee JW, Mukerji SS, Newey CR, Pathmanathan J, Abdennadher M, Casassa C, Gaspard N, Goldenholz DM, Gilmore EJ, Jing J, Kim JA, Kimchi EY, Ladha HS, Tobochnik S, Zafar S, Hirsch LJ, Westover MB, Shafi MM.
Ann Neurol, 2021. PubMed
Clinical Electroencephalography Findings and Considerations in Hospitalized Patients With Coronavirus SARS-CoV-2
Ayub N, Cohen J, Jing J, Jain A, Tesh R, Mukerji SS, Zafar SF, Westover MB, Kimchi EY.
Neurohospitalist, 2021. PubMed
Hospital complications among older adults: Better processes could reduce the risk of delirium
Moura Junior V, Westover MB, Li F, Kimchi E, Kennedy M, Benson NM, Moura LM, Hsu J.
Health Serv Manage Res, 2021. PubMed
Evaluation and Management of Delirium
Ryan SL, Kimchi EY.
Semin Neurol, 2021. PubMed
A functional topography within the cholinergic basal forebrain for encoding sensory cues and behavioral reinforcement outcomes
Robert B, Kimchi EY, Watanabe Y, Chakoma T, Jing M, Li Y, Polley DB.
Elife, 2021. PubMed
ICU delirium burden predicts functional neurologic outcomes
Paixao L, Sun H, Hogan J, Hartnack K, Westmeijer M, Neelagiri A, Zhou DW, McClain LM, Kimchi EY, Purdon PL, Akeju O, Westover MB.
PLoS One, 2021. PubMed
2020
A roadmap to advance delirium research: Recommendations from the NIDUS Scientific Think TankOh ES, Akeju O, Avidan MS, Cunningham C, Hayden KM, Jones RN, Khachaturian AS, Khan BA, Marcantonio ER, Needham DM, Neufeld KJ, Rose L, Spence J, Tieges Z, Vlisides P, Inouye SK; NIDUS Writing Group.
Alzheimers Dement, 2020. PubMed
Clinical Electroencephalography Findings and Considerations in Hospitalized Patients with Coronavirus SARS-CoV-2
Ayub N, Cohen J, Jing J, Jain A, Tesh R, Mukerji SS, Zafar SF, Westover MB, Kimchi EY.
medRxiv, 2020. PubMed
Accurate detection of spontaneous seizures using a generalized linear model with external validation
Fumeaux NF, Ebrahim S, Coughlin BF, Kadambi A, Azmi A, Xu JX, Abou Jaoude M, Nagaraj SB, Thomson KE, Newell TG, Metcalf CS, Wilcox KS, Kimchi EY, Moraes MFD, Cash SS.
Epilepsia, 2020. PubMed
CRMP-5-IgG Associated Paraneoplastic Chorea
Vaswani PA, Kimchi EY, Hung AY.
Mov Disord Clin Pract, 2020. PubMed
OpBox: Open Source Tools for Simultaneous EEG and EMG Acquisition from Multiple Subjects
Kimchi EY, Coughlin BF, Shanahan BE, Piantoni G, Pezaris J, Cash SS.
eNeuro, 2020. PubMed
2019
Postoperative Delirium and Postoperative Cognitive Dysfunction: Overlap and DivergenceDaiello LA, Racine AM, Yun Gou R, Marcantonio ER, Xie Z, Kunze LJ, Vlassakov KV, Inouye SK, Jones RN, Alsop D, Travison T, Arnold S, Cooper Z, Dickerson B, Fong T, Metzger E, Pascual-Leone A, Schmitt EM, Shafi M, Cavallari M, Dai W, Dillon ST, McElhaney J, Guttmann C, Hshieh T, Kuchel G, Libermann T, Ngo L, Press D, Saczynski J, Vasunilashorn S, O’Connor M, Kimchi E, Strauss J, Wong B, Belkin M, Ayres D, Callery M, Pomposelli F, Wright J, Schermerhorn M, Abrantes T, Albuquerque A, Bertrand S, Brown A, Callahan A, D’Aquila M, Dowal S, Fox M, Gallagher J, Anna Gersten R, Hodara A, Helfand B, Inloes J, Kettell J, Kuczmarska A, Nee J, Nemeth E, Ochsner L, Palihnich K, Parisi K, Puelle M, Rastegar S, Vella M, Xu G, Bryan M, Guess J, Enghorn D, Gross A, Gou Y, Habtemariam D, Isaza I, Kosar C, Rockett C, Tommet D, Gruen T, Ross M, Tasker K, Gee J, Kolanowski A, Pisani M, de Rooij S, Rogers S, Studenski S, Stern Y, Whittemore A, Gottlieb G, Orav J, Sperling R; SAGES Study Group*.
Anesthesiology, 2019. PubMed
Clinical EEG slowing correlates with delirium severity and predicts poor clinical outcomes
Kimchi EY, Neelagiri A, Whitt W, Sagi AR, Ryan SL, Gadbois G, Groothuysen D, Westover MB.
Neurology, 2019. PubMed
Automated tracking of level of consciousness and delirium in critical illness using deep learning
Sun H, Kimchi E, Akeju O, Nagaraj SB, McClain LM, Zhou DW, Boyle E, Zheng WL, Ge W, Westover MB.
NPJ Digit Med, 2019. PubMed
A cortical-brainstem circuit predicts and governs compulsive alcohol drinking
Siciliano CA, Noamany H, Chang CJ, Brown AR, Chen X, Leible D, Lee JJ, Wang J, Vernon AN, Vander Weele CM, Kimchi EY, Heiman M, Tye KM.
Science, 2019. PubMed
2018
Dopamine enhances signal-to-noise ratio in cortical-brainstem encoding of aversive stimuliVander Weele CM, Siciliano CA, Matthews GA, Namburi P, Izadmehr EM, Espinel IC, Nieh EH, Schut EHS, Padilla-Coreano N, Burgos-Robles A, Chang CJ, Kimchi EY, Beyeler A, Wichmann R, Wildes CP, Tye KM.
Nature, 2018. PubMed
2017
Amygdala inputs to prefrontal cortex guide behavior amid conflicting cues of reward and punishmentBurgos-Robles A, Kimchi EY, Izadmehr EM, Porzenheim MJ, Ramos-Guasp WA, Nieh EH, Felix-Ortiz AC, Namburi P, Leppla CA, Presbrey KN, Anandalingam KK, Pagan-Rivera PA, Anahtar M, Beyeler A, Tye KM.
Nat Neurosci, 2017. PubMed
Longitudinal diffusion changes following postoperative delirium in older people without dementia
Cavallari M, Dai W, Guttmann CRG, Meier DS, Ngo LH, Hshieh TT, Fong TG, Schmitt E, Press DZ, Travison TG, Marcantonio ER, Jones RN, Inouye SK, Alsop DC; SAGES Study Group.
Neurology, 2017. PubMed
Consensus Approaches to Identify Incident Dementia in Cohort Studies: Systematic Review and Approach in the Successful Aging after Elective Surgery Study
Kimchi EY, Hshieh TT, Guo R, Wong B, O’Connor M, Marcantonio ER, Metzger ED, Strauss J, Arnold SE, Inouye SK, Fong TG.
J Am Med Dir Assoc, 2017. PubMed
2015
American Geriatrics Society abstracted clinical practice guideline for postoperative delirium in older adultsAmerican Geriatrics Society Expert Panel on Postoperative Delirium in Older Adults.
J Am Geriatr Soc, 2015. PubMed
Postoperative delirium in older adults: best practice statement from the American Geriatrics Society
American Geriatrics Society Expert Panel on Postoperative Delirium in Older Adults.
J Am Coll Surg, 2015. PubMed
The American Geriatrics Society/National Institute on Aging Bedside-to-Bench Conference: Research Agenda on Delirium in Older Adults
AGS/NIA Delirium Conference Writing Group, Planning Committee and Faculty.
J Am Geriatr Soc, 2015. PubMed
Ageing delays emergence from general anaesthesia in rats by increasing anaesthetic sensitivity in the brain
Chemali JJ, Kenny JD, Olutola O, Taylor NE, Kimchi EY, Purdon PL, Brown EN, Solt K.
Br J Anaesth, 2015. PubMed
Streamlined, Inexpensive 3D Printing of the Brain and Skull
Naftulin JS, Kimchi EY, Cash SS.
PLoS One, 2015. PubMed
Seizures at the scale of individual neurons
Kimchi EY, Cash SS.
Brain, 2015. PubMed
The Successful Aging after Elective Surgery (SAGES) Study: Cohort Description and Data Quality Procedures
Schmitt EM, Saczynski JS, Kosar CM, Jones RN, Alsop DC, Fong TG, Metzger E, Cooper Z, Marcantonio ER, Travison T, Inouye SK; SAGES Study Group.
J Am Geriatr Soc, 2015. PubMed
2014
Delirium in elderly people–authors’replyInouye SK, Westendorp RG, Saczynski JS, Kimchi EY, Cleinman AA.
Lancet, 2014. PubMed
2013
Clinical Reasoning: a 44-year-old woman with headache followed by sudden neurologic declineBerkowitz AL, Kimchi EY, Hwang DY, Vaitkevicius H, Henderson GV, Feske SK, Chou SH.
Neurology, 2013. PubMed
2012
Impaired auditory discrimination learning following perinatal nicotine exposure or β2 nicotinic acetylcholine receptor subunit deletionHorst NK, Heath CJ, Neugebauer NM, Kimchi EY, Laubach M, Picciotto MR.
Behav Brain Res, 2012. PubMed
Transient aqueductal occlusion in intracerebral haemorrhage
Diamond EL, Kimchi EY, Shankar GM, Silverman SB.
Pract Neurol, 2012. PubMed
2009
Dynamic encoding of action selection by the medial striatumKimchi EY, Laubach M.
J Neurosci, 2009. PubMed
Neuronal correlates of instrumental learning in the dorsal striatum
Kimchi EY, Torregrossa MM, Taylor JR, Laubach M.
J Neurophysiol, 2009. PubMed
The dorsomedial striatum reflects response bias during learning
Kimchi EY, Laubach M.
J Neurosci, 2009. PubMed
2005
Redundancy and synergy of neuronal ensembles in motor cortexNarayanan NS, Kimchi EY, Laubach M.
J Neurosci, 2005. PubMed
2004
Dysregulation of sodium channel expression in cortical neurons in a rodent model of absence epilepsyKlein JP, Khera DS, Nersesyan H, Kimchi EY, Waxman SG, Blumenfeld H.
Brain Res, 2004. PubMed
2001
Analysis of cerebral amyloid angiopathy in a transgenic mouse model of Alzheimer disease using in vivo multiphoton microscopyKimchi EY, Kajdasz S, Bacskai BJ, Hyman BT.
J Neuropathol Exp Neurol, 2001. PubMed
Multiphoton microscopy and amyloid angiopathy
Christie R, Kimchi E, Kajdasz S, Bacskai B, Hyman BT.
Amyloid, 2001. PubMed
